(8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one - Names and Identifiers
Name | UnifiraM
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Synonyms | UnifiraM sunifiram DM-232 2-[(4-Fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one Pyrrolo[1,2-a]pyrazin-6(2H)-one, 2-[(4-fluorophenyl)sulfonyl]hexahydro- (8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one 2-(4-fluorophenyl)sulfonyl-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-one
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CAS | 272786-64-8
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(8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one - Physico-chemical Properties
Molecular Formula | C13H15FN2O3S
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Molar Mass | 298.3332032 |
Density | 1.47±0.1 g/cm3(Predicted) |
Boling Point | 479.5±55.0 °C(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Storage conditions Sealed in dry,2-8 c. acidity coefficient (pKa) -0.82±0.20(Predicted) |
(8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one - Introduction
UnifiraM is an organic compound, also known as UnifiraM. The following is a description of the nature, use, manufacture and safety information of the UnifiraM:
Nature:
-Appearance: colorless crystalline powder
-Molecular formula: C15H14FNO2S
-Molecular weight: 293.34g/mol
-Melting point: about 180-185°C
-Solubility: better solubility in organic solvents
Use:
UnifiraM have a variety of uses in medicinal chemistry and pharmaceutical research:
-As a synthetic intermediate: UnifiraM intermediates commonly used in the synthesis of other drug molecules, such as pyrrolopyrazine compounds.
-Anti-tumor activity: Some derivatives of UnifiraM have been studied and found to have potential anti-tumor activity and may have the potential to treat tumors.
Preparation Method:
At present, there is little detailed information about the preparation of UnifiraM, but it can usually be synthesized through a series of organic synthesis reactions. The method includes the synthesis of pyrrolopyrazine, reaction with 4-fluorobenzoyl chloride to yield an intermediate sulfonyl chloride compound, and synthesis of the final UnifiraM compound by ketonization.
Safety Information:
There is limited safety data on UnifiraM, so proper laboratory safety practices need to be followed when using or handling the compound. For any chemical, the relevant safety procedures should be closely followed, appropriate protective equipment should be worn, and good ventilation should be ensured. In addition, appropriate laboratory practices and regulations should be followed when using UnifiraM or compounds involving it.
Last Update:2024-04-09 21:54:55